Project Page Views: [ 665 ]
Project Metadata Element | Details |
Project Title | Genetic methods to improve Cr(VI) bioremediation in groundwater |
Research Area | Water |
Project Acronym | |
Principal Investigator or Lead Irish Partner | Enrico Marsili |
Lead Institution or Organisation | Dublin City University (DCU) |
Lead Country | Ireland |
Latitude, Longitude (of Lead Institution) | 53.38526, -6.25714 |
Lead Funding Entity | Environmental Protection Agency |
Approximate Project Start Date | 11/09/2008 |
Approximate Project Finishing Date | 11/09/2011 |
Project Website (if any) | |
Links to other Web-based resources | |
Project Keywords | Groundwater; Contamination; Bioremediation; Health |
Project Abstract | Cr(VI) contamination of groundwater and soils is a primary public health concern in Ireland. Bioremediation is an environmental-friendly salternative for Cr(VI) removal from groundwaterand soils, but Cr(VI) toxicity limits the efficiency of bioremediation. We will use for the first time genome shuffling techniques to improve Cr(VI) tolerance and Cr(VI) reduction capability of the strict anaerobic bacterium Geobacter metallireducens. We will investigate the mechanism of Cr(VI) reduction in the resulting G.metallireducens mutants through an innovative electrochemical approach. Finally, we will test the best performing mutants in a bench-scale Cr(VI) bioremediation process. |